Vascular endothelial growth factor A amplification in colorectal cancer is associated with reduced M1 and M2 macrophages and diminished PD-1-expressing lymphocytes

VEGFA is an angiogenic factor secreted by tumors, in particular those with VEGFA amplification, as well as by macrophages and lymphocytes in the tumor microenvironment. Here we sought to define the presence of M1/M2 macrophages, PD-1-positive lymphocytes and PD-L1 tumoral and stromal expression in c...

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Detalles Bibliográficos
Autores principales: Burmeister, Katharina, Quagliata, Luca, Andreozzi, Mariacarla, Eppenberger-Castori, Serenella, Matter, Matthias S., Perrina, Valeria, Grobholz, Rainer, Jochum, Wolfram, Horber, Daniel, Moosmann, Peter, Lehmann, Frank, Köberle, Dieter, Ng, Charlotte K. Y., Piscuoglio, Salvatore, Tornillo, Luigi, Terracciano, Luigi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389821/
https://www.ncbi.nlm.nih.gov/pubmed/28403223
http://dx.doi.org/10.1371/journal.pone.0175563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389821/
https://www.ncbi.nlm.nih.gov/pubmed/28403223
http://dx.doi.org/10.1371/journal.pone.0175563

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