A derivative of platelet-derived growth factor receptor alpha binds to the trimer of human cytomegalovirus and inhibits entry into fibroblasts and endothelial cells

Human cytomegalovirus (HCMV) is a widely distributed herpesvirus that causes significant morbidity in immunocompromised hosts. Inhibitors of viral DNA replication are available, but adverse effects limit their use. Alternative antiviral strategies may include inhibition of entry. We show that solubl...

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Detalles Bibliográficos
Autores principales: Stegmann, Cora, Hochdorfer, Daniel, Lieber, Diana, Subramanian, Narmadha, Stöhr, Dagmar, Laib Sampaio, Kerstin, Sinzger, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389858/
https://www.ncbi.nlm.nih.gov/pubmed/28403220
http://dx.doi.org/10.1371/journal.ppat.1006273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389858/
https://www.ncbi.nlm.nih.gov/pubmed/28403220
http://dx.doi.org/10.1371/journal.ppat.1006273

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