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A derivative of platelet-derived growth factor receptor alpha binds to the trimer of human cytomegalovirus and inhibits entry into fibroblasts and endothelial cells
Human cytomegalovirus (HCMV) is a widely distributed herpesvirus that causes significant morbidity in immunocompromised hosts. Inhibitors of viral DNA replication are available, but adverse effects limit their use. Alternative antiviral strategies may include inhibition of entry. We show that solubl...
Autores principales: | Stegmann, Cora, Hochdorfer, Daniel, Lieber, Diana, Subramanian, Narmadha, Stöhr, Dagmar, Laib Sampaio, Kerstin, Sinzger, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389858/ https://www.ncbi.nlm.nih.gov/pubmed/28403220 http://dx.doi.org/10.1371/journal.ppat.1006273 |
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