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GM-CSF produced by the airway epithelium is required for sensitization to cockroach allergen

Airway epithelial cells are among the first to encounter inhaled allergens and can initiate allergic responses by producing pro-Th2 innate cytokines. In this study, we investigated the role of epithelial-derived cytokines in sensitization to a clinically relevant allergen, cockroach allergen (CRA)....

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Detalles Bibliográficos
Autores principales: Sheih, Alyssa, Parks, William C., Ziegler, Steven F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389932/
https://www.ncbi.nlm.nih.gov/pubmed/27731325
http://dx.doi.org/10.1038/mi.2016.90