Single-cell sequencing and tumorigenesis: improved understanding of tumor evolution and metastasis

Extensive genomic and transcriptomic heterogeneity in human cancer often negatively impacts treatment efficacy and survival, thus posing a significant ongoing challenge for modern treatment regimens. State-of-the-art DNA- and RNA-sequencing methods now provide high-resolution genomic and gene expres...

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Detalles Bibliográficos
Autores principales: Ellsworth, Darrell L., Blackburn, Heather L., Shriver, Craig D., Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Ellsworth, Rachel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389955/
https://www.ncbi.nlm.nih.gov/pubmed/28405930
http://dx.doi.org/10.1186/s40169-017-0145-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389955/
https://www.ncbi.nlm.nih.gov/pubmed/28405930
http://dx.doi.org/10.1186/s40169-017-0145-6

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