Cortical Spreading Depression Causes Unique Dysregulation of Inflammatory Pathways in a Transgenic Mouse Model of Migraine

Familial hemiplegic migraine type 1 (FHM1) is a rare monogenic subtype of migraine with aura caused by mutations in CACNA1A that encodes the α(1A) subunit of voltage-gated Ca(V)2.1 calcium channels. Transgenic knock-in mice that carry the human FHM1 R192Q missense mutation (‘FHM1 R192Q mice’) exhibi...

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Detalles Bibliográficos
Autores principales: Eising, Else, Shyti, Reinald, ’t Hoen, Peter A. C., Vijfhuizen, Lisanne S., Huisman, Sjoerd M. H., Broos, Ludo A. M., Mahfouz, Ahmed, Reinders, Marcel J. T., Ferrari, Michel D., Tolner, Else A., de Vries, Boukje, van den Maagdenberg, Arn M. J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390001/
https://www.ncbi.nlm.nih.gov/pubmed/27032388
http://dx.doi.org/10.1007/s12035-015-9681-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390001/
https://www.ncbi.nlm.nih.gov/pubmed/27032388
http://dx.doi.org/10.1007/s12035-015-9681-5

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