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Roles of tau protein in health and disease

Tau is well established as a microtubule-associated protein in neurons. However, under pathological conditions, aberrant assembly of tau into insoluble aggregates is accompanied by synaptic dysfunction and neural cell death in a range of neurodegenerative disorders, collectively referred to as tauop...

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Detalles Bibliográficos
Autores principales: Guo, Tong, Noble, Wendy, Hanger, Diane P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390006/
https://www.ncbi.nlm.nih.gov/pubmed/28386764
http://dx.doi.org/10.1007/s00401-017-1707-9