Immunological memory to hyperphosphorylated tau in asymptomatic individuals

Several reports have described the presence of antibodies against Alzheimer’s disease-associated hyperphosphorylated forms of tau in serum of healthy individuals. To characterize the specificities that can be found, we interrogated peripheral IgG(+) memory B cells from asymptomatic blood donors for...

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Detalles Bibliográficos
Autores principales: Pascual, Gabriel, Wadia, Jehangir S., Zhu, Xueyong, Keogh, Elissa, Kükrer, Başak, van Ameijde, Jeroen, Inganäs, Hanna, Siregar, Berdien, Perdok, Gerrard, Diefenbach, Otto, Nahar, Tariq, Sprengers, Imke, Koldijk, Martin H., der Linden, Els C. Brinkman-van, Peferoen, Laura A., Zhang, Heng, Yu, Wenli, Li, Xinyi, Wagner, Michelle, Moreno, Veronica, Kim, Julie, Costa, Martha, West, Kiana, Fulton, Zara, Chammas, Lucy, Luckashenak, Nancy, Fletcher, Lauren, Holland, Trevin, Arnold, Carrie, Anthony Williamson, R., Hoozemans, Jeroen J., Apetri, Adrian, Bard, Frederique, Wilson, Ian A., Koudstaal, Wouter, Goudsmit, Jaap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390017/
https://www.ncbi.nlm.nih.gov/pubmed/28341999
http://dx.doi.org/10.1007/s00401-017-1705-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390017/
https://www.ncbi.nlm.nih.gov/pubmed/28341999
http://dx.doi.org/10.1007/s00401-017-1705-y

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