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Spine Enlargement of Pyramidal Tract-Type Neurons in the Motor Cortex of a Rat Model of Levodopa-Induced Dyskinesia

Growing evidence suggests that abnormal synaptic plasticity of cortical neurons underlies levodopa-induced dyskinesia (LID) in Parkinson's disease (PD). Spine morphology reflects synaptic plasticity resulting from glutamatergic transmission. We previously reported that enlargement of the dendri...

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Detalles Bibliográficos
Autores principales: Ueno, Tatsuya, Nishijima, Haruo, Ueno, Shinya, Tomiyama, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390020/
https://www.ncbi.nlm.nih.gov/pubmed/28450828
http://dx.doi.org/10.3389/fnins.2017.00206