Cargando…

Lineage Specification from Prostate Progenitor Cells Requires Gata3-Dependent Mitotic Spindle Orientation

During prostate development, basal and luminal cell lineages are generated through symmetric and asymmetric divisions of bipotent basal cells. However, the extent to which spindle orientation controls division symmetry or cell fate, and the upstream factors regulating this process, are still elusive...

Descripción completa

Detalles Bibliográficos
Autores principales: Shafer, Maxwell E.R., Nguyen, Alana H.T., Tremblay, Mathieu, Viala, Sophie, Béland, Mélanie, Bertos, Nicholas R., Park, Morag, Bouchard, Maxime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390093/
https://www.ncbi.nlm.nih.gov/pubmed/28285879
http://dx.doi.org/10.1016/j.stemcr.2017.02.004