Latexin Inactivation Enhances Survival and Long-Term Engraftment of Hematopoietic Stem Cells and Expands the Entire Hematopoietic System in Mice

Natural genetic diversity offers an important yet largely untapped resource to decipher the molecular mechanisms regulating hematopoietic stem cell (HSC) function. Latexin (Lxn) is a negative stem cell regulatory gene identified on the basis of genetic diversity. By using an Lxn knockout mouse model...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Zhang, Cuiping, Li, Zhenyu, Wang, Chi, Jia, Jianhang, Gao, Tianyan, Hildebrandt, Gerhard, Zhou, Daohong, Bondada, Subbarao, Ji, Peng, St. Clair, Daret, Liu, Jinze, Zhan, Changguo, Geiger, Hartmut, Wang, Shuxia, Liang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390104/
https://www.ncbi.nlm.nih.gov/pubmed/28330618
http://dx.doi.org/10.1016/j.stemcr.2017.02.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390104/
https://www.ncbi.nlm.nih.gov/pubmed/28330618
http://dx.doi.org/10.1016/j.stemcr.2017.02.009

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