MAD2L2 Promotes Open Chromatin in Embryonic Stem Cells and Derepresses the Dppa3 Locus

The chromatin of naive embryonic stem cells (ESCs) has a largely open configuration, as evident by the lack of condensed heterochromatin and the hypomethylation of DNA. Several molecular mechanisms promoting this constellation were previously identified. Here we present evidence for an important epi...

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Detalles Bibliográficos
Autores principales: Rahjouei, Ali, Pirouz, Mehdi, Di Virgilio, Michela, Kamin, Dirk, Kessel, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390107/
https://www.ncbi.nlm.nih.gov/pubmed/28330620
http://dx.doi.org/10.1016/j.stemcr.2017.02.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390107/
https://www.ncbi.nlm.nih.gov/pubmed/28330620
http://dx.doi.org/10.1016/j.stemcr.2017.02.011

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