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Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic Steatosis

Hepatic steatosis is a highly prevalent liver disease, yet research is hampered by the lack of tractable cellular and animal models. Steatosis also occurs in cats, where it can cause severe hepatic failure. Previous studies demonstrate the potential of liver organoids for modeling genetic diseases....

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Detalles Bibliográficos
Autores principales: Kruitwagen, Hedwig S., Oosterhoff, Loes A., Vernooij, Ingrid G.W.H., Schrall, Ingrid M., van Wolferen, Monique E., Bannink, Farah, Roesch, Camille, van Uden, Lisa, Molenaar, Martijn R., Helms, J. Bernd, Grinwis, Guy C.M., Verstegen, Monique M.A., van der Laan, Luc J.W., Huch, Meritxell, Geijsen, Niels, Vries, Robert G., Clevers, Hans, Rothuizen, Jan, Schotanus, Baukje A., Penning, Louis C., Spee, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390114/
https://www.ncbi.nlm.nih.gov/pubmed/28344000
http://dx.doi.org/10.1016/j.stemcr.2017.02.015