Cargando…

Inducible and Deterministic Forward Programming of Human Pluripotent Stem Cells into Neurons, Skeletal Myocytes, and Oligodendrocytes

The isolation or in vitro derivation of many human cell types remains challenging and inefficient. Direct conversion of human pluripotent stem cells (hPSCs) by forced expression of transcription factors provides a potential alternative. However, deficient inducible gene expression in hPSCs has compr...

Descripción completa

Detalles Bibliográficos
Autores principales: Pawlowski, Matthias, Ortmann, Daniel, Bertero, Alessandro, Tavares, Joana M., Pedersen, Roger A., Vallier, Ludovic, Kotter, Mark R.N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390118/
https://www.ncbi.nlm.nih.gov/pubmed/28344001
http://dx.doi.org/10.1016/j.stemcr.2017.02.016