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Nkx2-5 and Sarcospan genetically interact in the development of the muscular ventricular septum of the heart

The muscular ventricular septum separates the flow of oxygenated and de-oxygenated blood in air-breathing vertebrates. Defects within it, termed muscular ventricular septal defects (VSDs), are common, yet less is known about how they arise than rarer heart defects. Mutations of the cardiac transcrip...

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Detalles Bibliográficos
Autores principales: Panzer, Adam A., Regmi, Suk D., Cormier, DePorres, Danzo, Megan T., Chen, Iuan-bor D., Winston, Julia B., Hutchinson, Alayna K., Salm, Diana, Schulkey, Claire E., Cochran, Rebecca S., Wilson, David B., Jay, Patrick Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390293/
https://www.ncbi.nlm.nih.gov/pubmed/28406175
http://dx.doi.org/10.1038/srep46438