Myostatin mediates abdominal aortic atherosclerosis progression by inducing vascular smooth muscle cell dysfunction and monocyte recruitment

Myostatin (Mstn) is a skeletal muscle growth inhibitor involved in metabolic disorders and heart fibrosis. In this study we sought to verify whether Mstn is also operative in atherosclerosis of abdominal aorta. In human specimens, Mstn expression was almost absent in normal vessels, became detectabl...

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Detalles Bibliográficos
Autores principales: Verzola, D., Milanesi, S., Bertolotto, M., Garibaldi, S., Villaggio, B., Brunelli, C., Balbi, M., Ameri, P., Montecucco, F., Palombo, D., Ghigliotti, G., Garibotto, G., Lindeman, J. H., Barisione, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390310/
https://www.ncbi.nlm.nih.gov/pubmed/28406165
http://dx.doi.org/10.1038/srep46362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390310/
https://www.ncbi.nlm.nih.gov/pubmed/28406165
http://dx.doi.org/10.1038/srep46362

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