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ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway

Cancer cells are frequently confronted with metabolic stress in tumor microenvironments due to their rapid growth and limited nutrient supply. Metabolic stress induces cell death through ROS-induced apoptosis. However, cancer cells can adapt to it by altering the metabolic pathways. AMPK and AKT are...

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Detalles Bibliográficos
Autores principales: Zhao, Yang, Hu, Xingbin, Liu, Yajing, Dong, Shumin, Wen, Zhaowei, He, Wanming, Zhang, Shuyi, Huang, Qiong, Shi, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390360/
https://www.ncbi.nlm.nih.gov/pubmed/28407774
http://dx.doi.org/10.1186/s12943-017-0648-1