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The Krüppel-like factor 9 cistrome in mouse hippocampal neurons reveals predominant transcriptional repression via proximal promoter binding

BACKGROUND: Krüppel-like factor 9 (Klf9) is a zinc finger transcription factor that functions in neural cell differentiation, but little is known about its genomic targets or mechanism of action in neurons. RESULTS: We used the mouse hippocampus-derived neuronal cell line HT22 to identify genes regu...

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Detalles Bibliográficos
Autores principales: Knoedler, Joseph R., Subramani, Arasakumar, Denver, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390390/
https://www.ncbi.nlm.nih.gov/pubmed/28407733
http://dx.doi.org/10.1186/s12864-017-3640-7