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Amyloid precursor protein, lipofuscin accumulation and expression of autophagy markers in aged bovine brain
BACKGROUND: Autophagy is a highly regulated process involving the bulk degradation of cytoplasmic macromolecules and organelles in mammalian cells via the lysosomal system. Dysregulation of autophagy is implicated in the pathogenesis of many neurodegenerative diseases and integrity of the autophagos...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390414/ https://www.ncbi.nlm.nih.gov/pubmed/28407771 http://dx.doi.org/10.1186/s12917-017-1028-1 |