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Amyloid precursor protein, lipofuscin accumulation and expression of autophagy markers in aged bovine brain

BACKGROUND: Autophagy is a highly regulated process involving the bulk degradation of cytoplasmic macromolecules and organelles in mammalian cells via the lysosomal system. Dysregulation of autophagy is implicated in the pathogenesis of many neurodegenerative diseases and integrity of the autophagos...

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Detalles Bibliográficos
Autores principales:	De Biase, D., Costagliola, A., Pagano, T.B., Piegari, G., Wojcik, S., Dziewiątkowski, J., Grieco, E., Mattace Raso, G., Russo, V., Papparella, S., Paciello, O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390414/ https://www.ncbi.nlm.nih.gov/pubmed/28407771 http://dx.doi.org/10.1186/s12917-017-1028-1

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