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Exosomal transfer of tumor-associated macrophage-derived miR-21 confers cisplatin resistance in gastric cancer cells
BACKGROUND: Cisplatin-based chemotherapy is frequently used to treat advanced gastric cancer (GC). However, the resistance often occurs with the mechanisms being not well understood. Recently, emerging evidence indicates that tumor-associated macrophages (TAMs) play an important role in chemoresista...
Autores principales: | Zheng, Peiming, Chen, Lei, Yuan, Xiangliang, Luo, Qin, Liu, Yi, Xie, Guohua, Ma, Yanhui, Shen, Lisong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390430/ https://www.ncbi.nlm.nih.gov/pubmed/28407783 http://dx.doi.org/10.1186/s13046-017-0528-y |
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