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Klotho ameliorates oxidized low density lipoprotein (ox-LDL)-induced oxidative stress via regulating LOX-1 and PI3K/Akt/eNOS pathways

BACKGROUND: Atherosclerosis is a common cardiovascular disease that causes myocardial infarction, heart failure, and stroke. Increased oxidized low density lipoprotein (ox-LDL) in the sub-endothelium is the characteristic origin of atherogenesis. Klotho, an anti-aging protein, has been reported to p...

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Detalles Bibliográficos
Autores principales: Yao, Yansheng, Wang, Yanbing, Zhang, Yibo, Liu, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390438/
https://www.ncbi.nlm.nih.gov/pubmed/28407763
http://dx.doi.org/10.1186/s12944-017-0447-0