Plant Proteinase Inhibitor BbCI Modulates Lung Inflammatory Responses and Mechanic and Remodeling Alterations Induced by Elastase in Mice

Background. Proteinases play a key role in emphysema. Bauhinia bauhinioides cruzipain inhibitor (BbCI) is a serine-cysteine proteinase inhibitor. We evaluated BbCI treatment in elastase-induced pulmonary alterations. Methods.  C57BL/6 mice received intratracheal elastase (ELA group) or saline (SAL g...

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Detalles Bibliográficos
Autores principales: Almeida-Reis, Rafael, Theodoro-Junior, Osmar A., Oliveira, Bruno T. M., Oliva, Leandro V., Toledo-Arruda, Alessandra C., Bonturi, Camila R., Brito, Marlon V., Lopes, Fernanda D. T. Q. S., Prado, Carla M., Florencio, Ariana C., Martins, Mílton A., Owen, Caroline A., Leick, Edna A., Oliva, Maria L. V., Tibério, Iolanda F. L. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390602/
https://www.ncbi.nlm.nih.gov/pubmed/28466019
http://dx.doi.org/10.1155/2017/8287125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390602/
https://www.ncbi.nlm.nih.gov/pubmed/28466019
http://dx.doi.org/10.1155/2017/8287125

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