Cargando…

Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe

Redox imbalance in cells induces lipid peroxidation and generates a class of highly reactive metabolites known as lipid-derived electrophiles (LDEs) that can modify proteins and affects their functions. Identifying targets of LDEs is critical to understand how such modifications are functionally imp...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Ying, Cong, Yan, Quan, Baiyi, Lan, Tong, Chu, Xiaoyu, Ye, Zi, Hou, Xiaomeng, Wang, Chu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390668/
https://www.ncbi.nlm.nih.gov/pubmed/28411555
http://dx.doi.org/10.1016/j.redox.2017.04.001