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Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe
Redox imbalance in cells induces lipid peroxidation and generates a class of highly reactive metabolites known as lipid-derived electrophiles (LDEs) that can modify proteins and affects their functions. Identifying targets of LDEs is critical to understand how such modifications are functionally imp...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390668/ https://www.ncbi.nlm.nih.gov/pubmed/28411555 http://dx.doi.org/10.1016/j.redox.2017.04.001 |