Restoring visual function to the blind retina with a potent, safe and long-lasting photoswitch

Photoswitch compounds such as DENAQ confer light-sensitivity on endogenous neuronal ion channels, enabling photocontrol of neuronal activity without genetic manipulation. DENAQ treatment restores both retinal light responses and visual behaviors in rodent models of Retinitis pigmentosa. However, ret...

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Detalles Bibliográficos
Autores principales: Tochitsky, Ivan, Trautman, Jay, Gallerani, Nicholas, Malis, Jonatan G., Kramer, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390669/
https://www.ncbi.nlm.nih.gov/pubmed/28406473
http://dx.doi.org/10.1038/srep45487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390669/
https://www.ncbi.nlm.nih.gov/pubmed/28406473
http://dx.doi.org/10.1038/srep45487

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