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Role of p16(INK4a) and BMI-1 in oxidative stress-induced premature senescence in human dental pulp stem cells
Human dental pulp stem cells (hDPSCs) are a source for cell therapy. Before implantation, an in vitro expansion step is necessary, with the inconvenience that hDPSCs undergo senescence following a certain number of passages, loosing their stemness properties. Long-term in vitro culture of hDPSCs at...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390672/ https://www.ncbi.nlm.nih.gov/pubmed/28410532 http://dx.doi.org/10.1016/j.redox.2017.04.002 |