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Role of p16(INK4a) and BMI-1 in oxidative stress-induced premature senescence in human dental pulp stem cells

Human dental pulp stem cells (hDPSCs) are a source for cell therapy. Before implantation, an in vitro expansion step is necessary, with the inconvenience that hDPSCs undergo senescence following a certain number of passages, loosing their stemness properties. Long-term in vitro culture of hDPSCs at...

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Detalles Bibliográficos
Autores principales: Mas-Bargues, Cristina, Viña-Almunia, José, Inglés, Marta, Sanz-Ros, Jorge, Gambini, Juan, Ibáñez-Cabellos, José Santiago, García-Giménez, José Luis, Viña, José, Borrás, Consuelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390672/
https://www.ncbi.nlm.nih.gov/pubmed/28410532
http://dx.doi.org/10.1016/j.redox.2017.04.002