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High reward expectancy during methylphenidate depresses the dopaminergic response to gain and loss

Dopamine plays an important role in goal-directed behavior, through its modulatory influence on striatal neurons. It is unclear whether tonic dopamine levels, which regulate the vigor of acting, interact with the phasic dopamine response to reward that drives instrumental behavior. In a randomized p...

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Detalles Bibliográficos
Autores principales: Evers, E.A., Stiers, P., Ramaekers, J.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390715/
https://www.ncbi.nlm.nih.gov/pubmed/27677943
http://dx.doi.org/10.1093/scan/nsw124