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Fluorogenic sensor platform for the histone code using receptors from dynamic combinatorial libraries
Post-translational modifications (PTMs) on histone tails act in diverse combinations in the ‘histone code’ to control gene expression, with dysregulation observed in a variety of diseases. However, detection and sensing methods are limited, expensive, and/or low-throughput, including MS and antibody...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390788/ https://www.ncbi.nlm.nih.gov/pubmed/28451282 http://dx.doi.org/10.1039/c6sc03003c |