Targeted Fluoro Positioning for the Discovery of a Potent and Highly Selective Matrix Metalloproteinase Inhibitor

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The incorporation of fluorine atoms into functional molecules is of wide interest in synthetic organic chemistry as well as cognate disciplines. In particular, in medicinal chemistry, there is a strong desire to positively influence the physicochemical molecular properties of drug compounds by intro...

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Detalles Bibliográficos
Autores principales: Fischer, Thomas, Riedl, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390795/
https://www.ncbi.nlm.nih.gov/pubmed/28413749
http://dx.doi.org/10.1002/open.201600158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390795/
https://www.ncbi.nlm.nih.gov/pubmed/28413749
http://dx.doi.org/10.1002/open.201600158

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