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Highly efficient cell-type-specific gene inactivation reveals a key function for the Drosophila FUS homolog cabeza in neurons

To expand the rich genetic toolkit of Drosophila melanogaster, we evaluated whether introducing FRT or LoxP sites in endogenous genes could allow for cell-type-specific gene inactivation in both dividing and postmitotic cells by GAL4-driven expression of FLP or Cre recombinase. For proof of principl...

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Detalles Bibliográficos
Autores principales: Frickenhaus, Marie, Wagner, Marina, Mallik, Moushami, Catinozzi, Marica, Storkebaum, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390904/
https://www.ncbi.nlm.nih.gov/pubmed/25772687
http://dx.doi.org/10.1038/srep09107