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Ubiquitin and Parkinson's disease through the looking glass of genetics

Biochemical alterations found in the brains of Parkinson's disease (PD) patients indicate that cellular stress is a major driver of dopaminergic neuronal loss. Oxidative stress, mitochondrial dysfunction, and ER stress lead to impairment of the homeostatic regulation of protein quality control...

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Detalles Bibliográficos
Autores principales: Walden, Helen, Muqit, Miratul M.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390927/
https://www.ncbi.nlm.nih.gov/pubmed/28408429
http://dx.doi.org/10.1042/BCJ20160498