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From elementary flux modes to elementary flux vectors: Metabolic pathway analysis with arbitrary linear flux constraints

Elementary flux modes (EFMs) emerged as a formal concept to describe metabolic pathways and have become an established tool for constraint-based modeling and metabolic network analysis. EFMs are characteristic (support-minimal) vectors of the flux cone that contains all feasible steady-state flux ve...

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Detalles Bibliográficos
Autores principales: Klamt, Steffen, Regensburger, Georg, Gerstl, Matthias P., Jungreuthmayer, Christian, Schuster, Stefan, Mahadevan, Radhakrishnan, Zanghellini, Jürgen, Müller, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390976/
https://www.ncbi.nlm.nih.gov/pubmed/28406903
http://dx.doi.org/10.1371/journal.pcbi.1005409