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From elementary flux modes to elementary flux vectors: Metabolic pathway analysis with arbitrary linear flux constraints
Elementary flux modes (EFMs) emerged as a formal concept to describe metabolic pathways and have become an established tool for constraint-based modeling and metabolic network analysis. EFMs are characteristic (support-minimal) vectors of the flux cone that contains all feasible steady-state flux ve...
Autores principales: | Klamt, Steffen, Regensburger, Georg, Gerstl, Matthias P., Jungreuthmayer, Christian, Schuster, Stefan, Mahadevan, Radhakrishnan, Zanghellini, Jürgen, Müller, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390976/ https://www.ncbi.nlm.nih.gov/pubmed/28406903 http://dx.doi.org/10.1371/journal.pcbi.1005409 |
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