Bicaudal C mutation causes myc and TOR pathway up-regulation and polycystic kidney disease-like phenotypes in Drosophila

Progressive cystic kidney degeneration underlies diverse renal diseases, including the most common cause of kidney failure, autosomal dominant Polycystic Kidney Disease (PKD). Genetic analyses of patients and animal models have identified several key drivers of this disease. The precise molecular an...

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Detalles Bibliográficos
Autores principales: Gamberi, Chiara, Hipfner, David R., Trudel, Marie, Lubell, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390980/
https://www.ncbi.nlm.nih.gov/pubmed/28406902
http://dx.doi.org/10.1371/journal.pgen.1006694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390980/
https://www.ncbi.nlm.nih.gov/pubmed/28406902
http://dx.doi.org/10.1371/journal.pgen.1006694

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