Peptide probes derived from pertuzumab by molecular dynamics modeling for HER2 positive tumor imaging

A high level of HER2 expression in breast cancer correlates with a higher tumor growth rate, high metastatic potential, and a poor long-term patient survival rate. Pertuzumab, a human monoclonal antibody, can reduce the effect of HER2 overexpression by preventing HER2 dimerization. In this study, a...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoliang, Wang, Zihua, Xiang, Zhichu, Li, Dan, Hu, Zhiyuan, Cui, Wei, Geng, Lingling, Fang, Qiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390981/
https://www.ncbi.nlm.nih.gov/pubmed/28406988
http://dx.doi.org/10.1371/journal.pcbi.1005441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390981/
https://www.ncbi.nlm.nih.gov/pubmed/28406988
http://dx.doi.org/10.1371/journal.pcbi.1005441

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