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Predictive long-range allele-specific mapping of regulatory variants and target transcripts

Genome-wide association studies (GWASs) have identified a large number of noncoding associations, calling for systematic mapping to causal regulatory variants and their distal target genes. A widely used method, quantitative trait loci (QTL) mapping for chromatin or expression traits, suffers from s...

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Detalles Bibliográficos
Autores principales: Lee, Kibaick, Lee, Seulkee, Bang, Hyoeun, Choi, Jung Kyoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391085/
https://www.ncbi.nlm.nih.gov/pubmed/28406955
http://dx.doi.org/10.1371/journal.pone.0175768