A critical analysis of computational protein design with sparse residue interaction graphs

Protein design algorithms enumerate a combinatorial number of candidate structures to compute the Global Minimum Energy Conformation (GMEC). To efficiently find the GMEC, protein design algorithms must methodically reduce the conformational search space. By applying distance and energy cutoffs, the...

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Detalles Bibliográficos
Autores principales: Jain, Swati, Jou, Jonathan D., Georgiev, Ivelin S., Donald, Bruce R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391103/
https://www.ncbi.nlm.nih.gov/pubmed/28358804
http://dx.doi.org/10.1371/journal.pcbi.1005346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391103/
https://www.ncbi.nlm.nih.gov/pubmed/28358804
http://dx.doi.org/10.1371/journal.pcbi.1005346

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