Reconstruction of 3D structures of MET antibodies from electron microscopy 2D class averages

Dynamics of three MET antibody constructs (IgG1, IgG2, and IgG4) and the IgG4-MET antigen complex was investigated by creating their atomic models with an integrative experimental and computational approach. In particular, we used two-dimensional (2D) Electron Microscopy (EM) images, image class ave...

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Detalles Bibliográficos
Autores principales: Chen, Qi, Vieth, Michal, Timm, David E., Humblet, Christine, Schneidman-Duhovny, Dina, Chemmama, Ilan E., Sali, Andrej, Zeng, Wei, Lu, Jirong, Liu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391116/
https://www.ncbi.nlm.nih.gov/pubmed/28406969
http://dx.doi.org/10.1371/journal.pone.0175758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391116/
https://www.ncbi.nlm.nih.gov/pubmed/28406969
http://dx.doi.org/10.1371/journal.pone.0175758

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