Endocytosis of GluN2B-containing NMDA receptor mediates NMDA-induced excitotoxicity

N-methyl-D-aspartate (NMDA) receptor overactivation is involved in neuronal damage after stroke. However, the mechanism underlying NMDA receptor-mediated excitotoxicity remains unclear. In this study, we confirmed that excessive activation of NMDARs led to cell apoptosis in PC12 cells and in primary...

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Detalles Bibliográficos
Autores principales: Wu, Yu, Chen, Changwan, Yang, Qian, Jiao, Mingfei, Qiu, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391130/
https://www.ncbi.nlm.nih.gov/pubmed/28326942
http://dx.doi.org/10.1177/1744806917701921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391130/
https://www.ncbi.nlm.nih.gov/pubmed/28326942
http://dx.doi.org/10.1177/1744806917701921

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