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PRC2 is dispensable for HOTAIR‐mediated transcriptional repression

Long non‐coding RNAs (lncRNAs) play diverse roles in physiological and pathological processes. Several lncRNAs have been suggested to modulate gene expression by guiding chromatin‐modifying complexes to specific sites in the genome. However, besides the example of Xist, clear‐cut evidence demonstrat...

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Detalles Bibliográficos
Autores principales: Portoso, Manuela, Ragazzini, Roberta, Brenčič, Živa, Moiani, Arianna, Michaud, Audrey, Vassilev, Ivaylo, Wassef, Michel, Servant, Nicolas, Sargueil, Bruno, Margueron, Raphaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391141/
https://www.ncbi.nlm.nih.gov/pubmed/28167697
http://dx.doi.org/10.15252/embj.201695335