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Core engagement with β-arrestin is dispensable for agonist-induced vasopressin receptor endocytosis and ERK activation
G protein–coupled receptors (GPCRs) exhibit highly conserved activation and signaling mechanisms by which agonist stimulation leads to coupling of heterotrimeric G proteins and generation of second messenger response. This is followed by receptor phosphorylation, primarily in the carboxyl terminus b...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391177/ https://www.ncbi.nlm.nih.gov/pubmed/28228552 http://dx.doi.org/10.1091/mbc.E16-12-0818 |