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Contact guidance requires spatial control of leading-edge protrusion

In vivo, geometric cues from the extracellular matrix (ECM) are critical for the regulation of cell shape, adhesion, and migration. During contact guidance, the fibrillar architecture of the ECM promotes an elongated cell shape and migration along the fibrils. The subcellular mechanisms by which cel...

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Detalles Bibliográficos
Autores principales: Ramirez-San Juan, G. R., Oakes, P. W., Gardel, M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391181/
https://www.ncbi.nlm.nih.gov/pubmed/28228548
http://dx.doi.org/10.1091/mbc.E16-11-0769