Epigenetically repressing human cytomegalovirus lytic infection and reactivation from latency in THP-1 model by targeting H3K9 and H3K27 histone demethylases

Human Cytomegalovirus (hCMV) infects a broad range of the population and establishes life-long latency in the infected individuals. Periodically the latently infected virus can reactivate and becomes a significant cause of morbidity and mortality in immunocompromised individuals. In latent infection...

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Detalles Bibliográficos
Autores principales: Gan, Xin, Wang, Haifeng, Yu, Yanyan, Yi, Wei, Zhu, Shanshan, Li, En, Liang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391200/
https://www.ncbi.nlm.nih.gov/pubmed/28407004
http://dx.doi.org/10.1371/journal.pone.0175390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391200/
https://www.ncbi.nlm.nih.gov/pubmed/28407004
http://dx.doi.org/10.1371/journal.pone.0175390

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