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Discovery of novel determinants of endothelial lineage using chimeric heterokaryons

We wish to identify determinants of endothelial lineage. Murine embryonic stem cells (mESC) were fused with human endothelial cells in stable, non-dividing, heterokaryons. Using RNA-seq, it is possible to discriminate between human and mouse transcripts in these chimeric heterokaryons. We observed a...

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Detalles Bibliográficos
Autores principales: Wong, Wing Tak, Matrone, Gianfranco, Tian, XiaoYu, Tomoiaga, Simion Alin, Au, Kin Fai, Meng, Shu, Yamazoe, Sayumi, Sieveking, Daniel, Chen, Kaifu, Burns, David M, Chen, James K, Blau, Helen M, Cooke, John P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391207/
https://www.ncbi.nlm.nih.gov/pubmed/28323620
http://dx.doi.org/10.7554/eLife.23588