Investigation of triamterene as an inhibitor of the TGR5 receptor: identification in cells and animals

BACKGROUND: G-protein-coupled bile acid receptor 1 (GPBAR1, also known as TGR5) has been shown to participate in glucose homeostasis. In animal models, a TGR5 agonist increases incretin secretion to reduce hyperglycemia. Many agonists have been developed for clinical use. However, the effects of TGR...

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Detalles Bibliográficos
Autores principales: Li, Yingxiao, Cheng, Kai Chun, Niu, Chiang-Shan, Lo, Shih-Hsiang, Cheng, Juei-Tang, Niu, Ho-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391213/
https://www.ncbi.nlm.nih.gov/pubmed/28435224
http://dx.doi.org/10.2147/DDDT.S131892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391213/
https://www.ncbi.nlm.nih.gov/pubmed/28435224
http://dx.doi.org/10.2147/DDDT.S131892

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