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Sirt6 deficiency results in progression of glomerular injury in the kidney

Aging is associated with an increased incidence and prevalence of renal glomerular diseases. Sirtuin (Sirt) 6, a nicotinamide adenine dinucleotide (NAD)-dependent histone deacetylase, has been shown to protect against multiple age-associated phenotypes; however it is unknown whether Sirt6 has a dire...

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Detalles Bibliográficos
Autores principales: Huang, Wen, Liu, Hua, Zhu, Shuang, Woodson, Michael, Liu, Rong, Tilton, Ronald G., Miller, Jordan D., Zhang, Wenbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391219/
https://www.ncbi.nlm.nih.gov/pubmed/28351995
http://dx.doi.org/10.18632/aging.101214