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Physiological frailty index (PFI): quantitative in-life estimate of individual biological age in mice

The development of healthspan-extending pharmaceuticals requires quantitative estimation of age-related progressive physiological decline. In humans, individual health status can be quantitatively assessed by means of a frailty index (FI), a parameter which reflects the scale of accumulation of age-...

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Detalles Bibliográficos
Autores principales: Antoch, Marina P., Wrobel, Michelle, Kuropatwinski, Karen K., Gitlin, Ilya, Leonova, Katerina I., Toshkov, Ilia, Gleiberman, Anatoli S., Hutson, Alan D., Chernova, Olga B., Gudkov, Andrei V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391222/
https://www.ncbi.nlm.nih.gov/pubmed/28325885
http://dx.doi.org/10.18632/aging.101206