Lesion complexity drives age related cancer susceptibility in human mammary epithelial cells

Exposures to various DNA damaging agents can deregulate a wide array of critical mechanisms that maintain genome integrity. It is unclear how these processes are impacted by one's age at the time of exposure and the complexity of the DNA lesion. To clarify this, we employed radiation as a tool...

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Detalles Bibliográficos
Autores principales: Sridharan, Deepa M., Enerio, Shiena, LaBarge, Mark A., Stampfer, Martha M., Pluth, Janice M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391225/
https://www.ncbi.nlm.nih.gov/pubmed/28245431
http://dx.doi.org/10.18632/aging.101183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391225/
https://www.ncbi.nlm.nih.gov/pubmed/28245431
http://dx.doi.org/10.18632/aging.101183

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