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Lesion complexity drives age related cancer susceptibility in human mammary epithelial cells
Exposures to various DNA damaging agents can deregulate a wide array of critical mechanisms that maintain genome integrity. It is unclear how these processes are impacted by one's age at the time of exposure and the complexity of the DNA lesion. To clarify this, we employed radiation as a tool...
Autores principales: | Sridharan, Deepa M., Enerio, Shiena, LaBarge, Mark A., Stampfer, Martha M., Pluth, Janice M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391225/ https://www.ncbi.nlm.nih.gov/pubmed/28245431 http://dx.doi.org/10.18632/aging.101183 |
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