Silencing of the small GTPase DIRAS3 induces cellular senescence in human white adipose stromal/progenitor cells

Inhibition of Akt-mTOR signaling protects from obesity and extends life span in animals. In the present study, we analyse the impact of the small GTPase, GTP-binding RAS-like 3 (DIRAS3), a recently identified weight-loss target gene, on cellular senescence in adipose stromal/progenitor cells (ASCs)...

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Detalles Bibliográficos
Autores principales: Ejaz, Asim, Mattesich, Monika, Zwerschke, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391236/
https://www.ncbi.nlm.nih.gov/pubmed/28316325
http://dx.doi.org/10.18632/aging.101197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391236/
https://www.ncbi.nlm.nih.gov/pubmed/28316325
http://dx.doi.org/10.18632/aging.101197

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